Organic Chemistry by Graham Patrick
Author:Graham Patrick [Patrick, Graham]
Language: eng
Format: epub
ISBN: 9780191077869
Publisher: Oxford University Press
Published: 2017-02-02T00:00:00+00:00
Preclinical trials and formulation
Preclinical trials involve testing the drug candidate for selectivity, toxicity, and possible side effects. Most of this work is carried out by toxicologists, pharmacologists, and biochemists. However, organic chemists are needed to synthesize samples of the drug containing a radioisotope such as 14C. Such radiolabelled compounds are used to monitor the distribution and metabolism of the drug during in vivo tests.
Formulation involves pharmacists and pharmaceutical chemists who identify how best to store and administer the drug, for example as a pill or capsule.
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